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Session I: HOW THE INNATE IMMUNE SYSTEM MEDIATES THE RECOGNITION AND
CONTROL OF THE IMMUNE RESPONS
Innate immune sensing and its dissection with forward genetic methods
Bruce Beutler
Innate natural killer cell control of viral infections
Wayne M. Yokoyama
Signaling in the innate and adaptive immune response
Richard A. Flavell
TLR4 Signaling: Turning it on and turning it off
Stefanie N. Vogel
Session II: IDENTIFICATION AND ANALYSIS OF GENES PREDISPOSING TO
AUTOIMMUNE DISORDERS.
Genetic Interactions Mediating SLE Pathogenesis
Edward K. Wakeland
Identification of genes contributing to autoimmune type 1 diabetes, a common complex disease
Linda S. Wicker, et al.
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African-Americans
Jorge R. Oksenberg
Session III: TURNING ON: LYMPHOCYTE ACTIVATION AND THE AFFERENT IMMUNE
RESPONSE.
Affinity/Avidity and co-receptors: CD8, a rheostat for T cells?
Jeffrey Frelinger, Samantha Elliott, Lucinda Hensley, Edward Collins and Robert Maile.
Characterization of signaling complexes at the T cell antigen receptor
Lawrence E. Samelson
New insights into TRAF functions in lymphocyte activation
Gail Bishop, Bruce Hostager, Ping Xie, Sokol Haxhinasto, Carissa Moore, Laura Stunz, Lisa Busch, Kevin Brown, and Jacob Simmons.
Structural basis for costimulation
Steven Almo
Session IV: TURNING OFF: DIVERSE TYPES OF REGULATORY CELLS IN THE
PREVENTION OF UNCONTROLLED IMM
CD8αα Mediates Selective Survival and Differentiation of CD8 Memory T Cell Precursors
Hilde Cheroutre
Foxp3 programs development and function of regulatory CD4 T cells
Alexander Y. Rudensky
Regulation of CD4-mediated autoaggression by B lymphocyte subsets
Jonathan Braun
Session V: HOST DEFENSE AND BIODEFENSE: ANALYZING AND AUGMENTING THE
RESPONSE TO INFECTION AGENT
How do Memory T Cells Really Protect Against Intracellular Bacteria?
Karen L. Elkins
Innate and adaptive immune responses to Listeria monocytogenes infection
Natalya Serbina, Phillip Wong and Eric G. Pamer
Inoculum dose and the control of the CD8+ T cell Response to Respiratory Virus Infection
Thomas J. Braciale
Protein Synthesis and the Generation of MHC Class I Peptide Ligands: Could Nature Really be This Inefficient?
Jonathan W. Yewdell
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