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Session I: HOW THE INNATE IMMUNE SYSTEM MEDIATES THE RECOGNITION AND
CONTROL OF THE IMMUNE RESPONS
Innate immune sensing and its dissection with forward genetic methods Bruce Beutler
Innate natural killer cell control of viral infections Wayne M. Yokoyama
Signaling in the innate and adaptive immune response Richard A. Flavell
TLR4 Signaling: Turning it on and turning it off Stefanie N. Vogel
Session II: IDENTIFICATION AND ANALYSIS OF GENES PREDISPOSING TO
AUTOIMMUNE DISORDERS.
Genetic Interactions Mediating SLE Pathogenesis Edward K. Wakeland
Identification of genes contributing to autoimmune type 1 diabetes, a common complex disease Linda S. Wicker, et al.
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African-Americans Jorge R. Oksenberg
Session III: TURNING ON: LYMPHOCYTE ACTIVATION AND THE AFFERENT IMMUNE
RESPONSE.
Affinity/Avidity and co-receptors: CD8, a rheostat for T cells? Jeffrey Frelinger, Samantha Elliott, Lucinda Hensley, Edward Collins and Robert Maile.
Characterization of signaling complexes at the T cell antigen receptor Lawrence E. Samelson
New insights into TRAF functions in lymphocyte activation Gail Bishop, Bruce Hostager, Ping Xie, Sokol Haxhinasto, Carissa Moore, Laura Stunz, Lisa Busch, Kevin Brown, and Jacob Simmons.
Structural basis for costimulation Steven Almo
Session IV: TURNING OFF: DIVERSE TYPES OF REGULATORY CELLS IN THE
PREVENTION OF UNCONTROLLED IMM
CD8αα Mediates Selective Survival and Differentiation of CD8 Memory T Cell Precursors Hilde Cheroutre
Foxp3 programs development and function of regulatory CD4 T cells Alexander Y. Rudensky
Regulation of CD4-mediated autoaggression by B lymphocyte subsets Jonathan Braun
Session V: HOST DEFENSE AND BIODEFENSE: ANALYZING AND AUGMENTING THE
RESPONSE TO INFECTION AGENT
How do Memory T Cells Really Protect Against Intracellular Bacteria? Karen L. Elkins
Innate and adaptive immune responses to Listeria monocytogenes infection Natalya Serbina, Phillip Wong and Eric G. Pamer
Inoculum dose and the control of the CD8+ T cell Response to Respiratory Virus Infection Thomas J. Braciale
Protein Synthesis and the Generation of MHC Class I Peptide Ligands: Could Nature Really be This Inefficient? Jonathan W. Yewdell
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