Midwinter Conference of Immunologists
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2006 Poster Abstracts
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    A
      T cell-specific conditional deletion reveals essential function of TGFβ1 in T cell homeostasis
      M. Azhar, M.Yin, R. Bommireddy, J. Q. Yang, S. A. Pawlowski, J. J. Duffy, L. P. Sanford, C. Grisham, G. P. Boivin, G. F. Babcock, R. R. Singh, and T. Doetschman   ... details
      Discovery of a pancreatic lipase in cytotoxic T lymphocytes.
      Bryce Alves, David Tamang, Chris Clark, Stephanie Fraser, Mark Lowe*, Doug Redelman, and Dorothy Hudig.   ... details
      Modeling T Cell Antigen Discrimination Based on Feedback Control of Digital ERK Responses(*)
      Gregoire Altan-Bonnet(1,2) & Ronald N. Germain (1)   ... details
      Presyndromic Detection of Host Response Biomarkers in a Mouse Cowpox Model
      Michael S. Ascher, Richard G. Langlois, Kenneth W. Turteltaub, Kevin S. McLoughlin and C. Rick Lyons   ... details
      DYNAMIC CHANGES IN MICROCHIMERISM FROM A WOMAN??S OWN MOTHER AND FETUS IN PERIPHERAL BLOOD MONONUCLEAR CELLS DURING PREGNANCY
      Kristina M. Adams, M.D., Joelle Lucas, B.A., Nathalie C. Lambert, Ph.D., Timothy D. Erickson,B.S., Wendy Leisenring, ScD, and J. Lee Nelson, M.D.   ... details
      Mechanism of Third Signal Cytokines, IL-12 and IFN-α/β, in Programming CTL Differentiation
      Pujya Agarwal and Matthew F. Mescher   ... details
      B
        A selective role for the Cav1.3 channel in TCR-mediated calcium influx in Th2 cells
        Abdallah Badou1, Wajahat Z. Mehal1, Jörg Striessnig3, and Richard A. Flavell1,2   ... details
        Maternal Microchimerism in Renal Injury, Inflammation and Regeneration
        Kendall M. Blair1, Jesus Lopez-Guisa1, Edward Fisher1, Richard Zager2,3, Anne M. Stevens1,4   ... details
        Self-antigen recognition causes T-cell activation and systemic inflammation in TGFβ1- deficient mice
        Ramireddy Bommireddy1, Leena J. Pathak 1, Jennifer Martin1, Gregory P. Boivin2, George F. Babcock3, 4, and Thomas Doetschman1   ... details
        C
          Autoreactive Pre-Plasma Cell Regulation
          Kara L. Conway, Donna A. Culton, and Stephen H. Clarke   ... details
          Dendritic cells and macrophages display surface Sm that constitutively destabilizes the BCR complex.
          Diane G. Carnathan, Michelle Borrero*, and Barbara J. Vilen.   ... details
          Differential BLyS Receptor Expression and Responsiveness Following B cell Surface Molecule Ligation
          Jenni E. Crowley and Michael P. Cancro   ... details
          Genome wide RNAi screen for components of an innate immune response
          John Cho, Yun-Cheol Kim, Sherie Morrison   ... details
          HIV-1 elicits a pDC dependent IFN-α response in the human thymus
          Arnaud D Colantonio1, Debbie Anisman-Posner1, Beverly Redsar1, Fabienne Ropers, Hergen Spits2,Bianca Blom2, Christel Uittenbogaart1   ... details
          Oligonucleotide-based Inhibitors of TLR -7, -8 and -9 and thePotential for the Treatment of Systemic Lupus Erythematosusir (SLE)
          Jean H. Chan1, Thea Meeker1, Josh Gregorio1, Shizuo Akira2, Robert L. Coffman1, and Franck J. Barrat1   ... details
          Plasmacytoid Dendritic Cell-Specific Receptor ILT7/FcεRIγ Inhibits Toll-Like Receptor-Induced Interferon Production
          Wei Cao1, David B. Rosen2, Tomoki Ito1, Laura Bover1, Gokuran Watanabe1, Li Zhang3,Lewis L. Lanier2 and Yong-Jun Liu1   ... details
          Quantitating and visualizing CD8 T cell response to the intracellular parasite T. gondii
          Tatyana Chtanova1*, Marie Schaeffer1, Marc-Jean Gubbels2, Boris Striepen2, Ellen Robey1   ... details
          D
            ENHANCING IMMUNOGENICITY BY LIMITING SUSCEPTIBILITY TO LYSOSOMAL PROTEOLYSIS
            Lelia Delamarre, Rachael Couture, Ira Mellman and E. Sergio Trombetta   ... details
            FucT4/7 deficient regulatory T cells suppress liver inflammation but fail to rescue Scurfy mice from skin and lung associated autoimmune disease.
            Jan C. Dudda, Blythe D. Sather, Dora Gyarmati and Daniel J. Campbell   ... details
            Imprinting of Unique Differentiation Programs in ??Latecomer? and ??Earlybird? CD8 T cells
            Warren N. D'Souza and Stephen M. Hedrick   ... details
            F
              Characterisation of CD4+CD25+ cells in parasitic helminth induced regulation
              Constance A.M. Finney1, Mark S. Wilson1,2, Matthew D. Taylor1, Rick M. Maizels1   ... details
              Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix
              Jennifer A. Fulcher , Sara Tajyar, Ernest L. Levroney , Mabel Pang, Linda G. Baum , and Benhur Lee    ... details
              G
                Dendritic cells from lupus-prone mice are defective in repressing immunoglobulin secretion
                Mileka R. Gilbert, Diane G. Carnathan, Patricia C. Cogswell, Albert S. Baldwin, Jr,and Barbara J. Vilen   ... details
                MHC class I-positive Dendritic Cells control CD8 T cell homeostasis and shape the repertoir of peripheral CD8 T cells in vivo
                Anton Gruber, Christine Ried and Thomas Brocker   ... details
                H
                  Generation of Protective HP CD8+ T-cells Requires CD4+ T-cell Help
                  Sara E. Hamilton*, Monika C. Wolkers1, Stephen P. Schoenberger1, and Stephen C. Jameson*+   ... details
                  A novel autoinhibitory function of C2-like domain of PKCθ in regulating T cell activation
                  Keitaro Hayashi, Amnon Altman   ... details
                  A PERI-OVULATORY PLASMA GLYCOPROTEIN ALTERS THE TRAFFICKING POTENTIAL OF CD56bright (NK) NATURAL KILLER CELLS
                  Kota Hatta1, Marianne J van den Heuvel2, Crystal Peralta3, B Anne Croy4 Victor K Han2.   ... details
                  Anti-HER2/neu-IFN-α fusion protein: a potent therapeutic for treatment of B cell lymphoma in vivo
                  Tzu-Hsuan Huang, Sherie L. Morrison   ... details
                  BCR Peptide-directed T Cell Help During a T-dependant Immune Response Results in Abortive Germinal Center Reactions.
                  Ryan A. Heiser,1 Christopher M. Snyder2, Lawrence J. Wysocki1   ... details
                  DAP12-mediated inhibition of Toll-like receptor responses
                  Jessica A. Hamerman1, Jessica Jarjoura1, Nadia K. Tchao1,3, Mary Beth Humphrey4,6, Mary C. Nakamura4,6, Clifford A. Lowell5, William E. Seaman4,6 and Lewis L. Lanier1,2.   ... details
                  Diminished Palmitoylation of the Linker for Activation of T cells (LAT) in Anergic T cells
                  Matthias Hundt1, Hiroki Tabata1, Myung-Shin Jeon1, Yuko Fukata2, Masaki Fukata2, and Amnon Altman1   ... details
                  Lack of an anti-parasitic effect of human chitotriosidase genotype in a malaria- and hookworm endemic region of Papua New Guinea
                  Andrew J. Hall1, Rupert Quinnell2, Shaun Morroll1, and Franco H. Falcone1   ... details
                  The Role of TCR-MHC Interactions in Driving the Maturation of Recent Thymic Emigrants
                  Evan Houston, Tamar Boursalian, Kristina Bavik, Gail Turk, Pamela Fink   ... details
                  K
                    Myeloproliferative disease (MPD) in Id2 deficient mice and the downregulation of Id2 mediated by Bcr-Abl
                    Jinkyung Ko, Richard R. Rivera, and Cornelis Murre,   ... details
                    Priming of lung innate immunity by CpG-ODN: Enhanced pulmonary protection to airborne pathogens
                    Melissa Kachura1, Alya Zolotorev1, Jennifer O. Lizcano1, Edith M. Hessel1, Jennifer Berger2, Kevin Harrod2, Sarah Davis3, Brian K. Tarkington3, Londa Berghaus3, Laurel J. Gershwin3, Dallas M. Hyde3, Robert L. Coffman1, Holger Kanzler1   ... details
                    Structure/Function analysis of the αβTCR/CD3 complex
                    Michael S. Kuhns and Mark M. Davis   ... details
                    L
                      Functional analysis of FOXP3
                      Jared E. Lopes1,2, Lisa A. Schubert3, Troy R. Torgerson4, Hans D. Ochs4 and Steve F. Ziegler1,2   ... details
                      Real-Time Imaging of Thymocyte-Dendritic Cell Interactions in an Intact Thymic lobes
                      Ena Ladi1, Tanja Schwickert2, Michel Nussenzweig2, and Ellen Robey1   ... details
                      M
                        A model for the study of MHC II presentation to antigen specific T cells in non-lymphoid tissue
                        James B. McLachlan and Marc K. Jenkins   ... details
                        A NOVEL PROTEIN INVOLVED IN THYMOCYTE DIFFERENTIATION
                        Anil Munshi, Marielena V. McGuire, Jeanette Ampudia and Nicholas R.J. Gascoigne   ... details
                        Autoreactive T Lymphocytes in Humans are Biased Toward a Th2 Cytokine Profile
                        Neelufar Mozaffarian1,2, Alice E. Wiedeman2, and Anne M. Stevens2,3   ... details
                        In Vivo Activity of Inhibitors of TLR7 and TLR9 in Normal and Pathological Contexts
                        Thea Meeker, Jean Chan, Josh Gregorio, Carlo Calacsan, Tracy Matray, Robert L. Coffman and Franck J.Barrat   ... details
                        Inositol (1,4,5) trisphosphate 3 kinase B regulates the development, tolerance and activation of B lymphocytes.
                        Andrew T. Miller, Yina H. Huang, Susan Sutton, Ben G. Wen, Karsten Sauer, and Michael P. Cooke*.   ... details
                        PD-1:PD-L1 interactions contribute to functional suppression of HBV-specific CTLs in the liver.
                        Holly Maier1, Masanori Isogawa1, Gordan J. Freeman2, Francis V. Chisari1   ... details
                        Stability of TH1/Tc1 commitment to an effector lineage
                        Meredith Mathis, SingSing Way, Jamie Schoenborn, Chris Wilson   ... details
                        T1/ST2 is a negative regulator of Th2 cell-mediated allergic pulmonary inflammation.
                        Niamh E. Mangan1, Astrid Lanoue2, Andrew McKenzie2 and Padraic G. Fallon1.   ... details
                        The role of DRAK2 in autoimmunity of the central nervous system
                        Maureen A. McGargill1, Ben G. Wen2, and Stephen M. Hedrick1   ... details
                        The size of the CD4 recall response is dependent on the original precursor number of antigen-specific cells.
                        Megan MacLeod, Eric S. Huseby, Frances Crawford, John W. Kappler, Philippa Marrack.   ... details
                        N
                          A radio-resistant cell in the lymph node mediates deletional tolerance of CD8 T cells for a skin antigen expressed in melanocytes and melanoma
                          Lisa A Nichols, Teresa A Colella, Yiming Chen, Victor H Engelhard   ... details
                          O
                            On the role of antigen persistence for CD4+ T cell responses
                            Reinhard Obst, Hisse-Martien van Santen, Christophe Benoist, and Diane Mathis   ... details
                            CEACAM1 expression in HL60 human acute promyelocytic leukemia cells under differentiation into neutrophil.
                            Munetaka Ozeki and John Shively   ... details
                            On the role of antigen persistence for CD4+ T cell responses
                            Reinhard Obst, Hisse-Martien van Santen, Christophe Benoist, and Diane Mathis   ... details
                            P
                              A PROTEOMIC APPROACH TO IDENTIFYING PEPTIDES WITH POTENTIAL TO PROMOTE TRAFFICKING OF NATURAL KILLER (NK) CELLS TO THE UTERUS
                              Crystal Peralta1, Marianne van den Heuvel2, Kota Hatta3, B. Anne Croy4, and Victor Han2.   ... details
                              ALX negatively regulates T cell activation
                              Claire E. Perchonock, Melissa C. Fernando, William J. Quinn III, Chau T. guyen, Jing Sun, Michael J. Shapiro, and Virginia Smith Shapiro   ... details
                              Identifying Novel Regulators of CD28 Signaling in T Cells
                              Anthony Pajerowski and Virginia Shapiro   ... details
                              Physiologic Modulation of Natural Killer Cell Activity As An Early Marker Of Alzheimer's Disease
                              P Prolo1, A Angeli2, A Dovio2, F Chiappelli1, P Perotti2, M Pautasso3, ML Sartori2, S Mussino2, M Santoro4, L Saba2, F Fantó4, C Mocellini5, MG Rosso5, M Peano5, M Borgognone5, E Grasso5   ... details
                              The sources and targets of IL-10 during DC-driven, polarised immune responses in vivo
                              Georgia Perona-Wright1, Stephen J. Jenkins1, Alison Crawford1,2, David Gray1, Edward J. Pearce3 and Andrew S. MacDonald1   ... details
                              Q
                                CTLA-4 blockade and GMCSF combination immunotherapy alters the intra-tumor balance of effector and regulatory T cells without directly interfering with regulatory T cell activity
                                Sergio A. Quezada*, Karl S. Peggs and James P. Allison,   ... details
                                R
                                  EXPRESSION OF ACTIVATION-INDUCED CYTIDINE DEAMINASE IS REGULATED BY CELL DIVISION, PROVIDING A MECHANISTIC BASIS FOR DIVISION-LINKED CLASS SWITCH RECOMBINATION.
                                  James S. Rush, Man Liu, Valerie H. Odegard, Shyam Unniraman, David G. Schatz.   ... details
                                  IL-6 regulates antigen-experienced B cells via an Erk-dependent mechanism
                                  Jennifer A. Rutan, Nikki J. Wagner, and Barbara J. Vilen   ... details
                                  Lectin-like transcript-1 (LLT1) is a ligand for the inhibitory human NKR-P1A receptor
                                  David B. Rosen*, Jayaram Bettadapura#, Mohammed Alsharifi#, Porunelloor A. Mathew^, Hilary S. Warren2, #, and Lewis L. Lanier2, 3*   ... details
                                  Lsc regulates Marginal-Zone B cell migration and adhesion and is required for the IgM T-dependent primary antibody response.
                                  Anatoly Rubtsov, Pamela Strauch, Roberta Pelanda and Raul M. Torres.   ... details
                                  S
                                    BR3 and TACI Differentially Mediate NF-κB Pathway Activation
                                    Jason Stadanlick, Jean Labriola Sholz, Juli Miller, and Michael Cancro   ... details
                                    Effects of GATA-3 downregulation in early T cell development
                                    Deirdre D. Scripture-Adams and Ellen V. Rothenberg   ... details
                                    IDENTIFICATION OF DISTAL REGULATORY ELEMENTS THAT GOVERN ANTIGEN-SPECIFIC IFN-γ PRODUCTION IN VIVO.
                                    Jamie Schoenborn1, 2, Maria Shnyreva1, Deanna Gilbertson1, Chris Wilson.   ... details
                                    Pivotal roles for the BAFF/BAFF-R and BAFF/TACI axes in B-cell responses analysed by new anti-human BAFF-R and TACI agonistic mAbs.
                                    Daisuke Sakurai   ... details
                                    Regulatory T cell Expression of CCR4 is required to Prevent Cutaneous & Pulmonary Inflammation
                                    Blythe D. Sather1,2, Dora Gyarmati1, Mike Miazgowicz2, Jason D. Fontenot2, Alexander Y. Rudensky2 & Daniel J. Campbell1,2   ... details
                                    Spontaneous T lymphocyte responses to a widespread endogenous antigen in a transgenic mouse prostate cancer model
                                    Peter A. Savage, Virginia A. Pedicord, and James P. Allison   ... details
                                    The role of il2rβ in Foxp3 Expression and Generation of TR cells
                                    David M. Soper1,2, Deborah J. Kasprowicz1, Steven F. Ziegler1,2   ... details
                                    Visualization of a Primary Anti-tumor Immune Response by Positron Emission Tomography
                                    Chengyi J. Shu*, Shuling Guo â? , Young J. Kim â?¡, Stephanie M. Shelly §, Amar Nijagal*, Pritha Ray¶,Sanjiv S. Gambhir¶, Caius G. Radu*, Owen N. Witte*,â? ,§   ... details
                                    T
                                      Discovery of a novel perforin inhibitor within cytotoxic granules that halts RBC lysis and reduces T lymphocyte killing.
                                      David L. Tamang, Bryce Alves, Viki Elliot, Stephanie Fraser, Doug Redelman, Dorothy Hudig.   ... details
                                      Molecular mechanisms of class switch recombination in aCD38-activated B cells.
                                      Yumiko Tsukamoto, Atushi Sato, and Kiyoshi Takatsu   ... details
                                      Rbb2, a new BALB/c locus on chromosome 12 that confers resistance to autoantibody production in FcgammaR2-/- mice.
                                      Tatyana N Tarasenko, Silvia Bolland   ... details
                                      V
                                        A novel gene involved in thymocyte differentiation.
                                        Sebastien Vallee, Anil Munshi, Jeanette Ampudia, Marielena V. McGuire, Paul Fallen, James Bradley, Nicholas R. J. Gascoigne.   ... details
                                        STAT5- mediated signals sustain a TCR-initiated gene expression program towards differentiation of CD8 T cell effectors
                                        Grégory VERDEIL1, Denis PUTHIER2, Catherine NGUYEN2, Anne-Marie SCHMITT-VERHULST1 and Nathalie AUPHAN-ANEZIN1   ... details
                                        W
                                          Calcium Signaling of T cells during Early Antigen Encounter in Intact Lymph Node
                                          1Sindy H. Wei, 1Olga Safrina, 2Ian Parker, and 1Michael Cahalan   ... details
                                          Effects of aging on the immune response to AChR, the autoantigen in myasthenia gravis
                                          Earlanda Williams, Sue Stacy, and Ellen Kraig   ... details
                                          The effect of UV irradiated CD4 T cells on CD8 T cells during contact hypersensitivity
                                          Liangchun Wang and Kristin Hogquist   ... details
                                          Y
                                            Altered peptide ligands induce delayed and reduced CD8:CD3ζ interaction ?? a role for CD8 in distinguishing ligand quality
                                            Pia Yachi, Jeanette Ampudia, Tomasz Zal and Nicholas R.J. Gascoigne   ... details
                                            Loss of a Treg Population in Diabetes Prone NOD mice
                                            Ellen Young, Carmen Wong, Roland Tisch, Robert Maile, Lucinda Hensley, Jeffrey Frelinger   ... details
                                            Z
                                              Circulating Cytokines/Chemokines and Neutrophils Function in Patients with Fibromyalgia Syndrome
                                              Zhifang Zhang, John E. Shively   ... details

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